Overview of Carcinoma (liver)
Liver carcinoma is characterized by presence of abnormal, cancerous cells in the liver. Liver carcinoma can be of two types, primary liver carcinoma and secondary liver carcinoma. Primary carcinoma of liver occurs when cancer begins in the liver. It originates in the cell of liver and is also termed as hepatocellular carcinoma. It is a rare condition. Secondary carcinoma occurs when cancer is present in another organ and spreads to liver, causing liver carcinoma. Liver cancer is common all around the world with high prevalence due to chronic liver diseases, such as hepatitis C and fatty liver disease. The cancerous cells in the liver damage and destruct the function of liver. Liver carcinoma can spread to nearby organs and cause deleterious health effects. Cancer can also arise in the ducts of the liver. This type of cancer is termed as cholangiocarcinoma.
Causes and Risk Factors of Carcinoma (liver)
The exact cause of liver carcinoma is unknown. However, liver cirrhosis plays an important role in initiation and progression of liver cancer. Damage and scarring of liver that lead to cirrhosis can occur due to different reasons, such as alcoholism, infection of hepatitis B or C or primary biliary cirrhosis. The presence of inherited disorder, for instance haemochromatosis that is characterized by accumulation of iron in the liver, can also lead to cirrhosis and thus cancer. Obesity and intake of unhealthy food can also lead to fatty liver disease, which is considered as a risk factor for liver carcinoma. Secondary carcinoma of liver can occur due to cancer that has metastasized from breast, lungs, stomach, pancreas or colon.
Signs and Symptoms of Carcinoma (liver)
The main symptoms of liver carcinoma include unexplained weight loss, loss of appetite, nausea, swelling in legs and feet, yellowing of skin and eyes, vomiting, itchy skin, fatigue, lethargy, bloating, pain in abdomen, abdominal swelling and mild fever.