Having allergies? Not sure about the cause – Elisa Systems - Food Allergen Test Kits could be the solution
Allergies pose a high risk to the health and well being of people in developed countries. Allergies are abnormal immunologic response of your body to a foreign substance. The allergic reactions affect various systems such as the skin, airway, and digestive tract and manifest as rhinitis, urticaria, angioedema, eczema, vomiting, diarrhea and anaphylaxis which can be life threatening.
Several chronic conditions can be contributed by delayed allergies including: migraines, autoimmune problems, lupus, fibromyalgia, asthma, diabetes, thyroiditis and rheumatoid arthritis. In case, you are bothered by allergies affecting various body systems and not sure what is causing them, then Elisa Systems - Food Allergen Test Kits could provide you the solution. It can be the first step on your path to wellness when foods or chemicals that are taxing your immune system are identified.
How is ELISA testing done?
The type of functional antibody and specific reactive allergens are focused by testing for your delayed acquired sensitivities or allergies. Allergies reflect your bodily immune response to allergens. The ELISA systems using the advanced Lymphocyte Responsive Assays (LRA) test for reactive or harmful antibodies which are burden on your immune system. They measure reactions just as they occur in the body.
ELISA testing is a cell culture done on a sample of whole blood. The separated serum is incubated together with purified antigens. Then, the reaction is read to determine reactivity of your lymphocytes against the antigens. To determine precisely to which items your body reacts, each antigen is tested separately.
Uses of ELISA testing
ELISA testing is the most comprehensive and specific test in determining and addressing the concealed causes of several common health concerns. Information regarding foods or chemicals to which you are tolerant and allergic or sensitive to is provided by this test. Its detects your allergy or sensitivity to various substances such as:
- Foods and their additives/preservatives
- Danders, hairs and feathers
- Environmental chemicals and toxic minerals
- Therapeutic herbs
Types of food allergy and their testing
Type I – Type I allergy occurs in response to some foods and is generally found in children. It occurs as an immediate response to even small amounts of the allergic food, varying in intensity from mild to severe form. IgG antibody assays are used to assess this type of allergy.
Type II – Type II allergy involves lectin allergens found in legumes, grains and some vegetables. They bind to receptors on your red blood cells, mucous membranes, intestinal lining and most other cells, attracting IgG antibodies and killer cells, which will destroy red blood cells, leading to anemia. Cooking and digestion destroy most lectins and they rarely cause serious problems. This type of allergy can be evaluated by ELISA systems, detecting reactive immunoglobulin A (IgA) and IgG antibodies.
Type III – Type III allergy occurs when you have an excess of antibody IgG to a specific food. The IgG antibodies bind directly to the allergen food as it enters the bloodstream, forming different sizes of circulating immune complexes which may deposit in certain tissues, producing a Type III reaction. The symptoms usually take 2-24 hours to appear but may take longer than that. Large amounts and multiple types of food may be necessary to produce allergic symptoms. Since different types of food and delayed onset of symptoms are involved, you may find yourself making multiple visits to several physicians. ELISA systems make the accurate diagnosis for this condition.
An inter-laboratory study was conducted with commercially available peanut ELISA test kits to detect and quantify peanut residues in two food matrices namely biscuit and dark chocolate at four different concentrations 0–10 mg peanut per kg matrix corresponding to about 0–2.5 mg peanut protein per kg matrix. It was found that the five ELISA test kits evaluated could detect peanut protein in the two food matrices. Generally, all the ELISA test kits performed well in the concentration range 5–10 mg per kg rather than in the low concentration range of 2.0 or 2.5 mg per kg. The variation in the found recoveries of peanut between the different test kits had a spread of 44–191% across all concentrations. Likewise, ELISA test has proved beneficial in several similar studies, indicating its practical application in detecting allergies.
Type IV – Type IV allergy reactions are involved in case you have contact dermatitis, for instance with poison ivy, many autoimmune and infectious diseases. Metals used in medical and dental care, such as nickel, gold, palladium, and mercury can also trigger this type of allergy in your system during their use for therapeutic purposes or if you are accidentally exposed to them. These reactions are mediated by T cells in the skin and soft tissues, monocytes, and macrophages. The food allergens are trapped by macrophages and transferred to T cells that have had prior contact with the sensitizing allergen. The response of memory T cells is enlargement of cells or Lymphoblast transformation and dividing or proliferation of the cells. Chemicals such as Interleukins are released by these cells which stimulate the immune system, causing inflammation and tissue damage, leading to degenerative symptoms and facilitating the allergic reaction. The best solution for detection of this form of allergy is provided by ELISA systems.
You must consult your physician when your allergic symptoms are taking a toll on your health. Getting onto the root of your problem can pave the path of speedy recovery and well-being.