Sjögren's syndrome is a type of autoimmune disease that causes the mouth as well as the eyes to dry up. In the eyes, it can cause inflammation of the tear glands or the lacrimal glands, resulting in eye irritation. Tear production is also reduced, causing the “gritty” sensation common in Sjögren's syndrome. If the eye irritation isn’t addressed, it can lead to eye infections, abrasions of the cornea, as well as inflammation of the eyelids.

In the mouth, Sjögren's syndrome can cause inflammation of the salivary glands, resulting in decreased salivary production and dry mouth. This will not only make swallowing difficult but it can also lead to mouth problems like cavities as well as mouth sores. It’s also not unusual for people with Sjögren's syndrome to develop dry cough or hoarseness of the voice. Some patients even complain of the loss of sense of taste.